Сайт о бордоских догах
Фото Емперор Тор
Emperor Thor
Метки
pH желудочного сока собаки Бордоский дог Бордоский дог Емперор Тор ЖКТ собак Копроскопия Пребиотик Инулин анализ крови биохимический анализ крови биохимия крови бордоский дог Антей бордоский дог бесплатно бордоский дог ищет хозяина ветровки с бордоским догом видео бордоских догов выбор кроха или подросток выставка бордоских догов здоровье собак калорий собаке копрология кормление собак кормление щенка мнение о судьях найден бордос основные показатели собак отзвывы о Азен отзывы о судье Азен отзывы о судьях отзывы о экспертах отзывы о эксперте пищеварение собак показатели ЖКТ показатели крови правила получения титулов расстройство пищеварения у собак расчет калорий сколько давать корма сколько корма надо собаке сколько надо калорий собаке судья температура тела собак толстовки с бордоским догом фото бордоских догов щенок бордоского дога эксперт кинолог

Физиологические показатели собак


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Основные физиологические показатели у собак.

(по В.Н.Митину, 1992)

Показатели Щенок Взрослая собака Старая собака
Температура 38,5-39оС 38,5-39оС 38,5-39оС
Частота пульса 110 -120 уд/мин 90-100 уд/мин 70-80 уд/мин
Частота дыхтельных движений 18-20/мин 16-18/мин 14-16/мин
Содержание эритроцитов в 1 мм3 крови 6,2 млн 6,2 млн 6,2 млн
Содержание лейкоцитов в 1 мм3 крови 7-15 тысяч 7-15 тысяч 7-15 тысяч
Продолжительность кровотечения 3-5 мин 3-5 мин 3-5 мин
Время свертывания крови 4-8 мин 4-8 мин 4-8 мин
Удельный вес крови 1,05 1,05 1,05
Суточная выработка мочи 0,4-2,0 л 0,4-2,0 л 0,4-2,0 л
Удельный вес мочи 1,02-1,05 1,02-1,05 1,02-1,05
рН мочи 6-7 6-7 6-7

Нормы биохимических показателей сыворотки крови собак (по М.Филиппову, 2001)

Наименование Единица измерения Норма
Глюкоза Ммоль/л 3,3-6,0
Белок г/л 54-77
Альбумин г/л 25-37
Холестерин Ммоль/л 3,3-7,0
Билирубин общий Мкмоль/л 0-7,5
Аланинаминотрансфераза U/л 10-55
Аспартатаминотрансфераза U/л 10-55
Лактатдегидрогеназа U/л 50-495
Щелочная фосфатаза U/л 10-150
Гамма-глутамилтрансфераза U/л 1-10
Амилаза U/л 300-2000
Мочевина Ммоль/л 4,3-8,9
Креатинин Мкмоль/л 35-133
Фосфор неорганический Ммоль/л 0,7-1,8
Кальций Ммоль/л 2,0-2,7
Магний Ммоль/л 0,72-1,2
Мочевая кислота Мкмоль/л до 160 (по П.Ф.Сутеру,2001)
Триглицериды Ммоль/л 0,56 (по П.Ф.Сутеру2001)
Электролиты:
Калий (K+) Ммоль/л 4,0-5,7
Натрий (Na+) Ммоль/л 141-155
Хлориды (Cl) Ммоль/л 103-115

БИОХИМИЧЕСКИЙ АНАЛИЗ КРОВИ
1.Глюкоза -универсальный источник энергии для клеток — главное вещество, из которого любая клетка организма получает энергию для жизни.
Потребность организма в энергии, а значит — в глюкозе — увеличивается параллельно физической и психологической нагрузке под действием гормона стресса — адреналина, во время роста, развития, выздоровления (гормоны роста, щитовидной железы, надпочечников).
Cреднее значение для собак — 4.3-7.3 ммоль/л, кошек- 3.3-6.3 ммоль/л.
Для усвоения глюкозы клетками необходимо нормальное содержание инсулина — гормона поджелудочной железы.
При его недостатке (сахарный диабет) глюкоза не может пройти в клетки, ее уровень в крови повышен, а клетки голодают.
Повышение (гипергликемия):
— сахарный диабет (недостаточность инсулина)
— физическая или эмоциональная нагрузка (выброс адреналина)
— тиреотоксикоз (повышение функции щитовидной железы)
— синдром Кушинга (повышение уровня гормона надпочечников — кортизола)
— заболевания поджелудочной железы (панкреатит, опухоль, муковисцидоз)
— хронические заболевания печени, почек
Снижение (гипогликемия):
— голодание
— передозировка инсулина
— заболевания поджелудочной железы (опухоль из клеток, синтезирующих инсулин)
— опухоли (избыточное потребление глюкозы как энергетического материала опухолевыми клетками)
— недостаточность функции эндокринных желез (надпочечников, щитовидной, гипофиза (гормон роста))
— тяжелые отравления с поражением печени (алкоголем, мышьяком, соединениями хлора, фосфора, салицилатами, антигистаминами)

2.Общий белок«Жизнь — это способ существования белковых тел». Белки — главный биохимический критерий жизни. Они входят в состав всех анатомических структур (мышцы, клеточные мембраны), переносят вещества по крови и в клетки, ускоряют течение биохимических реакций в организме, распознают вещества — свои или чужие и защищают от чужих, регулируют обмен веществ, удерживают жидкость в кровеносных сосудах и не дают ей уходить в ткани.
Белки синтезируются в печени из аминокислот пищи. Общий белок крови состоит из двух фракций: альбумины и глобулины.
Cреднее для собак- 59-73 г/л,кошек — 54-77 г/л.
Повышение (гиперпротеинемия):
— обезвоживание (ожоги, диарея, рвота — относительное повышение концентрации белка за счет снижения объема жидкости)
— миеломная болезнь (избыточная продукция гамма-глобулинов)
Снижение (гипопротеинемия):
— голодание (полное или белковое — строгое вегетарианство, нервная анорексия)
— заболевания кишечника (нарушение всасывания)
— нефротический синдром ( почечная недостаточность)
— повышенное потребление (кровопотеря, ожоги, опухоли, асцит, хроническое и острое воспаление)
— хроническая печеночная недостаточность (гепатит, цирроз)

3.Альбумин
— одна из двух фракций общего белка — транспортная. Норма для собак- 22-39 г/л,кошек- 25-37 г/л.
Повышение (гиперальбуминемия): Истинной (абсолютной) гиперальбуминемии не бывает. Относительная возникает при снижении общего объема жидкости (обезвоживании)
Снижение (гипоальбуминемия): Те же, что и для общей гипопротеинемии.

4.Билирубин общий — компонент желчи, состоит из двух фракций — непрямого (несвязанного), образующегося при распаде клеток крови (эритроцитов), и прямого (связанного), образующегося из непрямого в печени и выводящегося через желчные протоки в кишечник.
Является красящим веществом (пигментом), поэтому при его повышении в крови изменяется окраска кожи — желтуха.

Повышение (гипербилирубинемия):
— повреждение печеночных клеток (гепатиты, гепатозы — паренхиматозная желтуха)
— непроходимость желчных протоков (механическая желтуха)

5.Мочевина
— продукт обмена белков, удаляющийся почками. Часть остается в крови.
Норма для собаки — 3-8.5 ммоль/л, для кошки — 4-10.5 ммоль/л.
Повышение:
— нарушение функции почек
— непроходимость мочевыводящих путей
— повышенное содержание белка в пище
— повышенное разрушение белка (ожоги, острый инфаркт миокарда) Снижение:
— белковое голодание
— избыточное потребление белка (беременность, акромегалия)
— нарушение всасывания

6.Креатинин
— конечный продукт метаболизма креатина,синтезируемого в почках и печени из трех аминокислот(аргинина,глицина,метионина).Полностью выделяется из организма почками путем клубочковой фильтрации,не реабсорбируясь в почечных канальцах.
Норма для собаки — 30-170 мкмоль/л.,кошки — 55-180 мкмоль/л.
Повышено:
— нарушение функции почек(почечная недостаточность)
— гипертиреоз
Понижено:
— беременность
— возрастные уменьшения мышечной массы

7.Аланинаминотрансфераза (АлАТ)
Фермент, вырабатываемый клетками печени, скелетных мышц и сердца.
Норма для собаки- 0-65 ЕД,

Повышение:
— разрушение клеток печени (некроз, цирроз, желтуха, опухоли )
— разрушение мышечной ткани (травма, миозит, мышечная дистрофия)
— ожоги
— токсическое действие на печень лекарств (антибиотиков и др)

8.Аспартатаминотрансфераза (АсАТ)
— Фермент вырабатываемый клетками сердца, печени, скелетных мышц и эритроцитами.
Среднее содержание у собак — 10-42 ЕД,.
Повышение:
— повреждение печеночных клеток (гепатит, токсическое повреждение лекарствами, метастазы в печень)
— тяжелая физическая нагрузка
— сердечная недостаточность
— ожоги, тепловой удар

9.Гамма-глутамилтрансфераза (Гамма-ГТ)
— Фермент, вырабатываемый клетками печени, поджелудочной железы, щитовидной железы.
собаки — 0-8 ЕД,кошки — 0-3 ЕД.
Повышение:
— забoлевания печени ( гепатит, цирроз, рак)
— заболевания поджелудочной железы (панкреатит, сахарный диабет)
— гипертиреоз (гиперфункция щитовидной железы) 10.Альфа-Амилаза
-Фермент, вырабатываемый клетками поджелудочной и околоушной слюнной желез.
Норма у собаки- 550-1700 ЕД, у кошки — 450-1550 ЕД.
Повышение:
— панкреатит (воспаление поджелудочной железы)
— паротит (воспаление околоушной слюнной железы)
— сахарный диабет
— заворот желудка и кишечника
— перитонит
Снижение:
— недостаточность функции поджелудочной железы
— тиреотоксикоз

Калий,натрий,хлориды
-Обеспечивают электрические свойства клеточных мембран.
По разные стороны клеточной мембраны специально поддерживается разница концентрации и заряда: натрия и хлоридов больше снаружи клетки, а калия внутри, но при этом меньше, чем натрия снаружи, — это создает разность потенциалов между сторонами клеточной мембраны — заряд покоя, который позволяет клетке быть живой и реагировать на нервные импульсы, участвуя в системной деятельности организма. Теряя заряд, клетка выбывает из системы, т.к. не может воспринимать команды мозга.
Т.о., натрий и хлориды — внеклеточные ионы, калий — внутриклеточный.
Кроме поддержания потенциала покоя, эти ионы принимают участие в генерации и проведении нервного импульса — потенциала действия.
Регуляция минерального обмена в организме (гормоны коры надпочечников) направлена на задержку натрия, которого не хватает в натуральной пище (без поваренной соли) и выведение калия из крови, куда он попадает при разрушении клеток.
Ионы вместе с другими растворенными веществами удерживают жидкость: цитоплазму внутри клеток, внеклеточную жидкость в тканях, кровь — в кровеносных сосудах, регулируя артериальное давление, предотвращая развитие отеков.
Хлориды входят в состав желудочного сока.

11.Калий: собаки — 3.6-5.5,
Повышение калия (гиперкалиемия):
— повреждение клеток (гемолиз — разрушение клеток крови, тяжелое голодание, судороги, тяжелые травмы)
— обезвоживание
— острая почечная недостаточность (нарушение выведения почками)
— гиперадренокортикоз
Снижение калия (гипокалиемия)
— хроническое голодание (непоступление с пищей)
— продолжительные рвота, понос (потеря с кишечным соком)
— нарушение функции почек
— избыток гормонов коры надпочечников (в т.ч. прием лекарственных форм кортизона)
— гипоадренокортикоз

12.Натрий собаки — 140-155,
Повышение натрия (гипернатриемия):
— избыточное потребление соли
— потеря внеклеточной жидкости ( тяжелая рвота и диарея, повышенное мочеотделение (несахарный диабет)
— избыточная задержка (повышенная функция коры надпочечников)
— нарушение центральной регуляции водно-солевого обмена (патология гипоталамуса, кома) Снижение натрия (гипонатриемия):
— потеря (злоупотребление мочегонными, патология почек, надпочечниковая недостаточность)
— снижение концентрации за счет повышения объема жидкости (сахарный диабет, хроническая сердечная недостаточность, цирроз печени, нефротический синдром, отеки)

13.Хлориды собаки – 105-122,
Повышение хлоридов:
— обезвоживание
— острая почечная недостаточность
— несахарный диабет
— отравление салицилатами
— повышенная функция коры надпочечников
Снижение хлоридов:
— профузный понос, рвота,
— увеличение объема жидкости

14.Кальций Собаки – 2.25-3 ммоль/л,

Участвует в проведении нервного импульса, особенно в сердечной мышце. Как все ионы, удерживает жидкость в сосудистом русле, препятствуя развитию отеков. Необходим для мышечного сокращения, свертывания крови. Входит в состав костной ткани и эмали зубов.
Уровень в крови регулируется гормоном паращитовидных желез и витамином Д. Паратгормон повышает уровень кальция в крови, вымывая из костей, увеличивая всасывание в кишечнике и задерживая выведение почками.
Повышение (гиперкальциемия):
— повышение функции паращитовидной железы
— злокачественные опухоли с поражением костей (метастазы, миелома, лейкозы)
— избыток витамина Д
— обезвоживание
Снижение (гипокальциемия):
— снижение функции щитовидной железы
— дефицит витамина Д
— хроническая почечная недостаточность
— дефицит магния

15.Фосфор неорганический
Собаки – 0.8-2.3, кошки – 0.9-2.3 ммоль/л.
Элемент, входящий в состав нуклеиновых кислот, костной ткани и основных систем энергообеспечения клетки — АТФ.
Регулируется параллельно с уровнем кальция.
Повышение:
— разрушение костной ткани (опухоли, лейкоз )
— избыток витамина Д
— заживление переломов
— эндокринные нарушения
— почечная недостаточность
Снижение:
— недостаток гормона роста
— дефицит витамина Д
— нарушение всасывания, тяжелый понос, рвота
— гиперкальциемия

16.Фосфатаза щелочная
Собаки – 0-100,кошки – 4-85 ЕД.
Фермент, образующийся в костной ткани, печени, кишечнике, плаценте, легких.
Повышение:
— беременность
— повышенный обмен в костной ткани (быстрый рост, заживление переломов, рахит, гиперпаратиреоз)
— заболевания костей (остеогенная саркома, метастазы рака в кости)
— заболевания печени Снижение:
— гипотиреоз (гипофункция щитовидной железы)
— анемия (малокровие)
— недостаток витамина С, В12, цинка, магния

ЛИПИДЫ
Липиды (жиры) — необходимые для живого организма вещества. Основной липид, который человек получает из пищи, и из которого затем образуются собственные липиды — холестерин. Он входит в состав клеточных мембран, поддерживает их прочность. Из него синтезируются т.н. стероидные гормоны: гормоны коры надпочечников, регулирующие водно-солевой и углеводный обмен, приспосабливающие организм к новым условиям; половые гормоны. Из холестерина образуются желчные кислоты, участвующие в усвоении жиров в кишечнике. Из холестерина в коже под действием солнечных лучей синтезируется витамин Д, необходимый для усвоения кальция.
При повреждении целостности сосудистой стенки и/или избытке холестерина в крови он осаждается на стенку и образует холестериновую бляшку. Это состояние называется атеросклероз сосудов: бляшки суживают просвет, мешают кровотоку, нарушают гладкость течения крови, усиливают свертываемость крови, способствуют образованию тромбов. В печени образуются различные комплексы липидов с белками, циркулирующие в крови: липопротеиды высокой, низкой и очень низкой плотности (ЛПВП, ЛПНП, ЛПОНП); общий холестерин поделен между ними. Липопротеиды низкой и очень низкой плотности осаждаются в бляшках и способствуют прогрессированию атеросклероза. Липопротеиды высокой плотности за счет наличия в них специального белка — апопротеина А1 — способствуют «вытягиванию» холестерина из бляшек и играют защитную роль, останавливают атеросклероз. Для оценки риска состояния важен не суммарный уровень общего холестерина, а соотношение его фракций.

17.Общий холестерин
Собаки – 2.9-8.3,кошки – 2-5.9 ммоль/л.
Повышение:
— заболевания печени
— гипотиреоз (недостаточность функции щитовидной железы)
— ишемическая болезнь сердца (атеросклероз)
— гиперадренокортицизм
Снижение:
— энтеропатии,сопровождающиеся потерей белка
— гепатопатии (портокавальный анастомоз ,цирроз)
— злокачественные новообразования
— плохое питание



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